Which class of drugs is primarily used to reduce the frequency of seizures?

Antiepileptics are the primary class of drugs used to reduce the frequency of seizures. These medications work by stabilizing electrical activity in the brain and can modulate neurotransmitter release. They target various mechanisms, such as enhancing inhibitory neurotransmission, inhibiting excitatory neurotransmission, or altering ion channel activity. This makes them effective in managing different types of epilepsy and preventing seizure occurrence.

While antidepressants and antipsychotics may have roles in managing associated symptoms or co-morbid conditions in patients with epilepsy, they do not directly target seizure prevention. Therefore, antiepileptics are specifically designed to address the underlying pathophysiology of seizure disorders, making them the standard treatment choice for reducing seizure frequency.