Identify a common side effect of SSRIs.

Sexual dysfunction is a well-documented and common side effect associated with the use of selective serotonin reuptake inhibitors (SSRIs). The mechanism behind this side effect is related to the way SSRIs increase serotonin levels in the brain, which can interfere with sexual arousal, desire, and performance. Many SSRIs inhibit sexual function by affecting neurotransmitters that play a role in the sexual response cycle.

Understanding that sexual dysfunction can manifest as decreased libido, difficulties with orgasm, or erectile dysfunction helps heed the concern many patients have when initiating treatment with SSRIs. This side effect is significant enough that healthcare providers often discuss it ahead of time with their patients to prepare them for possible experiences while on medication.

While other side effects like weight gain, sedation, or memory loss can occur with different classes of medications, they are not as consistently linked to SSRIs specifically. For instance, weight gain is more prominent in certain antidepressants but not as universally associated with SSRIs. Sedation may occur with some SSRIs but is not a defining feature, as many SSRIs are activating rather than sedating. Similarly, memory loss is more commonly associated with other classes of medications or conditions rather than being a hallmark side effect of SSRIs.